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A Journal on Surgery

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Chirurgia 2006 February;19(1):73-7

language: English

Solid and pseudo-papillary neoplasm arising from an ectopic pancreas. A case report

Bergamini C. 1, Borrelli A. 1, Presenti L. 1, De Giovanni M. 1, Comin C. 2, Valeri A. 1, Borrelli D. 1

1 Department of General and Vascular Surgery Careggi Hospital, Florence, Italy
2 Department of Human Pathology and Oncology University of Florence Medical School, Florence, Italy


A case of a solid-pseudopapillary neoplasm arising from an ectopic pancreas in the retroperitoneal tissue in a 40-year-old woman is presented. A 7.5-cm, well encapsulated tumor, adherent but not infiltrating the spleen and the upper left kidney was surgically resected. Hystologically, the tumor showed a solid and papillary pattern of polygonal epitheliod cells organized around a fibrovascular stalk. Most of the tumor cells had an eosinophil cytoplasm with focal aggregates of PAS positive hyaline globules and showed a positivity for vimentyn, (1-antitrypsin and (1-antichemotrypsin. All the tumor cells were negative for estrogens or progesterone receptors. The incidence of both ectopic pancreas outside of the gastrointestinal wall and solid and pseudo-papillary neoplasm of the pancreas is very rare. To our knowledge this is the 4th case reported in literature of an association between such 2 conditions.

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