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A Journal on Surgery
Indexed/Abstracted in: EMBASE, Scopus, Emerging Sources Citation Index
Chirurgia 2004 December;17(6):235-6
Unsolved problems in the management of squamous cell carcinoma of the anal canal. Case report
Salamina G., Migliorini L., Garbini A., Bertoncini M., Sarro G., Boldrini F., Poccobelli M., Rivolta U., Bragherio G.
In order to assess the unsolved problems in the management of carcinoma of the anal canal we examined a clinical case. In April 1999 a 49-year-old man underwent radiotherapy for a squamous cell carcinoma of the anal canal. In August 2001 he underwent abdominoperineal resection for recurrence of the disease. He died on March 2002 due to devastating perineal recurrence. At present, diagnosis of squamous cell carcinoma of the anal canal is obtained by incisional biopsy and fine needle aspiration or incisional biopsy too, in the presence of palpable lymph nodes. The stage of the disease is then assessed by endorectal ultrasonography and CT scan and/or MRI. Therapy could consist of radiotherapy or combined chemoradiotherapy. Abdominoperineal resection is performed for recurrence of the disease. We need to control timing and radiotherapy dose and we still need to assess the indications for correct treatment of this disease.