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A Journal on Surgery

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Chirurgia 2004 April;17(2):59-62

language: English

Hyperthyroid or functionally inactive ectopic mediastinal huge goiters

Cecere B., Cicalese M., Sorice M., De Luca G., Maietta P., Liberti D.


The clinical findings and surgical treatment of 3 patients with true mediastinal huge goiters were evaluated; there were 2 males and 1 female whose ages ranged from 48 to 75 years. Every patient complained cough and shorthness of breath. The 51-year-old woman showed hyperthyroidism and had edema of the head too; she underwent a left hemithyroidectomy for cervical goiter 30 years before; soon after admission her scintigraphy showed an intense accumulation of radioactivity corresponding to the intrathoracic goiter. Chest CT revealed a bulky anterior mediastinal mass without connection with cervical thyroid in every patient. In the younger patient, scintigraphy did not show a radioactive accumulation in the mediastinum; a cytologic diagnosis of ectopic goiter was made using a fine-needle biopsy. In the older patient, scintigraphy showed a moderate radioctive accumulation in the mediastinal mass. The mediastinal masses were removed through a median sternotomy with excellent results. Histologic examination revealed a multinodular goiter in all the cases.

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