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Chirurgia 2001 June-August;14(3-4):151-4

language: Italian

Primary intestinal lymphoma

Coli P.


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Ten cases of primary intestinal lymphoma were found in a period of 5 years. Most of them were located in the small intestine, the others in the large intestine. Specific criteria to define primary intestinal lymphoma and diagnostic procedure absolutely necessary to the diagnosis are emphasized. The treatment of primary intestinal lymphoma is not yet standardized. Surgery has an important role. It is necessary in emergency, when lymphoma manifest itself as a complication (for example occlusion, intussuception, perforation, etc.) and when there are complications due to radiation therapy and to chemotherapy. Surgery is the best treatment for lymphoma with a low grade of malignancy, whereas for these at high grade the validity of surgery hasn't been tested in controlled trials but there is evidence that also a limited removal is associated to a longer survival than the only conservative treatment. Surgery is important also for the diagnosis due to the difficulty of a preoperative diagnosis, especially for the localization in the small intestine. Surgery permits a sure histologic diagnosis and a stadiation of the disease. The role of radiotherapy is not yet clear, whereas the efficacy of chemotherapy treatment is accepted. Among small intestine tumors, the lymphomas have the best prognosis with a survival of five years between 33 and 78%.

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