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Chirurgia 2001 June-August;14(3-4):133-6

language: Italian

Factors contributing to leakage of colo-rectal anastomosis: personal observations and literature review

Nistri R., Vitali A., Basili G., Carrieri P.


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Background. Anastomotic leakage is one of the major causes of morbidity and mortality in surgery of the colon and rectum, being responsible for at least one third of the perioperative deaths. This complication seems also to be the second main risk-factor for cancer recurrencet (after the tumor stage). Two most important risk-factors for anastomotic leakage have been identified: preoperative radiotherapy and the site of the anastomosis.
Methods. The Authors have reviewed 100 patient submitted to radical surgery for rectal cancer in the last three years.
Results. Anastomotic leakage complicated the postoperative course in 6.3% of the patients, all of them being operated on for cancer of the lower rectum (less than 7 cm from the anal verge).
Conclusions. Among risk-factors for anastomotic leakage, the only one confirmed by personal experience was the distal level of resection.

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