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A Journal on Surgery

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Chirurgia 2001 February;14(1):63-6

language: Italian

Pseudotumor of pancreatic head

Cristiano S., Angelone G., Giardiello C.


A case of pseudotumor of the pancreatic head, a rare disease of surgical interest with particular problems of differential diagnosis, is described. A male patient, 43 ys old, was hospitalized with symptoms of acute abdomen. He had a history of gastroenteric disorders from several months, associated with a marked weight loss. He underwent both ultrasound and CT examination, showing an irregular enlargement of the head of the pancreas and therefore submitted to surgery. A pancreaticoduodenectomy was performed. Intraoperative histology indicated diffuse fibrosis of the pancreas and the absence of neoplasm. The postoperative course was regular and intraoperative diagnosis was confirmed by the pathologist. This case outlines the difficulties of the differential diagnosis between carcinoma and pseudotumor of the head of the pancreas as reported by Gulik et al.: in a series of 220 cases of pancreaticoduodenectomy performed for carcinoma of the head of the pancreas 14 (6%) cases of pseudotumor at histology have been found. The difficult differential diagnosis between inflammatory and neoplastic pancreatic disease and the central role played by intraoperative histology are underlined.

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