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Indexed/Abstracted in: EMBASE, Scopus, Emerging Sources Citation Index
Online ISSN 1827-1782
Ballari F., Arezzo A., Amorosa L., Coccia M. C., Cesaro S., De Gregori M.
Background. The high frequency of gallbladder carcinoma as occasional finding after cholecystectomy, suggested this retrospective research. During a period of 18 months, 212 laparotomic and laparoscopic cholecystectomies have been performed in our institute. The real high frequency of gallbladder carcinoma in our district, and its relation with risk factors are underlined and the potential precursors of invasive carcinoma are studied.
Methods. A total 11 cases of gallbladder carcinoma, 9 females and 2 males, middle age 81 years (70-92) have been observed, out of 212 cholecystectomies during a period of 18 months.
Results. Considering that several series denote a frequency of gallbladder carcinoma as occasional finding between 0.6 and 4.4%, excluding some peoples such as Maori and Native American Indians, our series is over the above range limit.
Conclusions. It is common opinion that this primitive carcinoma is rare, associated with a late diagnosis and poor prognosis, then it is necessary to consider its prevention, and the more important risk factors, first of all the gallstones. The drastic reduction of morbility and, although on a smaller scale, of the mortality due to laparoscopic therapy, compared to the traditional one, should allow a broad choice of surgical therapies for gallstones and its complications.