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A Journal on Surgery

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Chirurgia 2000 April;13(2):109-12

language: Italian

Meconium ileus complicated with perforation in a severely premature patient

Messina M., Meucci D., Di Maggio G., Ferrucci E., Leoni R., Laganà C.


Meconium ileus is a neonatal obstruction of the small intestine caused by thick and tenacious meconium. This syndrome may occur in either a simple or complicated form when associated with stenosis, volvulus, single or multiple atresia or pertoration. In 75% of cases, meconium ileus occurs in neonates suffering from cystic fibrosis; in 10-15% of cases in otherwise normal infants and, lastly, in 5% of cases in premature or small for date neonates weighing less than 1500 g. The authors present a case of meconium ileus complicated by intestinal perforation diagnosed in a severely premature neonate with a low birth weight (29 weeks gestation, 990 g). The infant presented severely damaged respiratory dynamics and a very severe hemodynamic decompensation as part of a syndrome of extreme septic shock.

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