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A Journal on Surgery
Indexed/Abstracted in: EMBASE, Scopus, Emerging Sources Citation Index
Chirurgia 2000 February;13(1):39-42
Carcinoid tumor of the rectum
Bombardieri T., Strati V., Cafiero C., Aspromonte N., Morabito C., Vasile R.
This extremely rare tumor of the rectum is part of the group of neuroendocrine malignancies. These tumors can produce a variety of substances biologically capable of provoking various clinical syndromes on the basis of the substance produced. Carcinoid tumors of the rectum, unlike those that developing in other sectors, are only occasionally productive. On the basis of a case recently observed a review of the literature on the subject is made and the biological peculiarities of this type of cancer are underlined: on one hand is less aggressive and has a longer period of latency as compared to the more frequent carcinoma, and on the other develops in a misleading but invasive way. Then, the most recent therapeutical protocols are reviewed, and although these are by now well codified and standardized, they can cause controverse opinions because of the limited number of cases and the scanty experience acquired in their treatment. Therefore, in the light of an adeguate surgical treatment and a more favourable prognostic evolution, the necessity of a careful evaluation of the more important pathologic parameteres and of an accurate pre-surgical grading of the tumor are underlined.