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A Journal on Surgery
Indexed/Abstracted in: EMBASE, Scopus, Emerging Sources Citation Index
Chirurgia 1999 December;12(6):415-8
Radical thyroidectomy and parathyroid function in thyroid malignancies. Functional implications
Giovannini C., Pirozzi R., Pronio A., Montesani C.
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Background. The incidence of thyroid malignancies is reported to be 4/100,000 per year in Caucasian population. For this kind of pathology a radical thyroidectomy must be performed in order to remove all thyroid tissue; nevertheless, despite extensive surgery is required, parathyroid glands must be maintained. The aim of this study was to evaluate the parathyroid function in patients who underwent total thyroidectomy for their thyroid malignancies.
Methods. 337 total thyroidectomies were performed in the period between 1990-1997, 60 of which were for thyroid malignancies (45 papillary ca., 8 follicular ca., 3 medullar ca., 2 poor differentiated ca., 2 non Hodgkin lymphomas). Monolateral or laterocervical lymphadenectomies were performed in 5 and 2 cases of thyroid malignancies, respectively. Ten cases of postoperative hypoparathyroidism, are presented: 1 of these with clinical evidence and 9 with both clinical and biological symptoms.
Results. Calcium plasma levels returned to normal values after the third postoperative day in 9 cases and after the tenth day in 1 case. No permanent in hypoparathyroidism or recurring lesions have been observed personal experience.
Conclusions. 131I scintigraphy of thyroid, performed 40 days after surgery demonstrated an uptake after 24 hours lower than 2%, indicating the absence of any detectable thyroid residual tissue.