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Chirurgia 1999 August;12(4):291-4

language: Italian

Effects of a diagnosis delay in the treatment and survival in patients with pancreatic neoplasms

Pantalone D., Bontà M., Allocca A., Nincheri M., Borri A.


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Background. Pancreatic cancer is a serious disease. The 5-year global survival varies between 1 to 5%. Surgery is the only curative treatment available for this cancer; it is justified only in selected patients with a less than 4 cm major diameter pancreatic neoplasm. In these patients, survival rate is about 30%. In this study many aspects are considered: the very difficult early diagnosis, the correct diagnostic process, the present surgical procedures and new trends in biologic and genetic research.
Methods. Seventy-seven patients have been operated on for pancreatic cancer over a twenty year period (1972-1993): 24.7% of them had a curative resection.
Results. Global 5-year survival was 31.5%. The other patients had a global 5-year survival rate of 5.2%.
Conclusions. These results suggest that more studies are necessary to define an «early pancreatic cancer» and how to detect it, in order to significantly improve the survival of these patients.

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