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Indexed/Abstracted in: EMBASE, Scopus, Emerging Sources Citation Index
Online ISSN 1827-1782
Borrelli A., Poma A., Valeri A., Presenti L., Petrolo A., Borrelli D.
Background.The results of survival in 47 patients are evaluated in relationship to cancer staging and surgical procedure performed.
Methods. Personal case-series regarding 47 patients affected by gallbladder cancer and submitted to surgery from 1984 to 1994 is presented. In the majority of patients radical surgery was not allowed except for those patients diagnosed in the first stages of disease, as also reported in the literature.
Results. All patients classified in stage I and II are still living, except for one patient in stage II who died 17 months later due to another pathology. Four patients in stage III lived for more than two years and two of these patients are still living. This last group was submitted to extended cholecystectomy. Three out of five stage IV patients lived more than two years, while only two out of twenty-five stage V patients lived for more than two years. In patients with a survival rate range of less than two years, only a slight difference was in patients submitted to a much more aggressive surgical procedure.
Conclusions. The conclusions is then drawn that a simple cholecystectomy may be acceptable in first stage disease, even though in stage II patients surgery should be extended to the gallbladder situs and to lymph nodes. This last procedure is strictly necessary in stage III cancer. Patients in stage IV and V do not report very long term survival neverthless a more advanced surgical procedure is adapted as reported by the majority of other authors.