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Indexed/Abstracted in: EMBASE, Scopus
Frequency: 3 issues
Online ISSN 1827-1790
Napoli V. 1, Napoli E. 2
1 Centro di Chirurgia del Piede, Clinica “Fornaca di Sessant”, Torino
2 Villa Maria Pia Hospital, Torino
The inflammatory reaction is the way the organism responds to surgical aggression for defensive purposes and to repair damage. But this very same reactivity can become damaging if the extent and gravity of the operative lesions prove greater than the body’s capacity for physiological reaction and induce a change in the response from beneficial to local and systemic aggressiveness. In foot surgery the possibility of such an event increases in so far as the inflammatory reaction induced in the site of the operation combines with that generated in the zone of hemostatic tourniquet pressure and above all in the area rendered ischaemic by this pressure. It is necessary and possible to avoid this risk by means of painstaking, rigorous application of preventive measures with two complementary approaches: 1) attentive surgical technique and diligent tourniquet management; 2) pharmacological modulation of the inflammatory reaction in support of the physiological effects and to counter the effects of the lesion.