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MEDICINA E CHIRURGIA DELLA CAVIGLIA E DEL PIEDE

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Chirurgia Del Piede 2007 December;31(3):161-5

Copyright © 2007 EDIZIONI MINERVA MEDICA

language: Italian

Prevention and treatment of adverse events by local anesthetics

Napoli V. 1, Napoli E. 2, Manno E. P. 3

1 Centro di Chirurgia del Piede Casa di Cura “Fornaca di Sessant”, Torino 2 Università degli Studi di Torino Facoltà di medicina e chirurgia Dipartimento di Discipline Medico Chirurgiche 3 ASL 3 Ospedale Maria Vittoria Dipartimento di Anestesia e Rianimazione, Torino


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Thanks to their noted effectiveness and manageability, local anesthetics are widely employed in surgical treatment; however, their use may induce adverse events, among which toxic effects and allergic reactions can sometimes lead to serious complications. Toxic effects are caused by overdosing of the anesthetic, resulting in elevated concentrations of the agent in the blood. Initial central nervous system symptoms manifest with irritation, but may also involve the cardiorespiratory system in more severe cases. Rarer but equally dangerous, allergic reactions are an immunologic response that is neither dose-dependent nor directly related to the pharmacologic properties of the anesthetic. To ensure patient safety in surgical procedures requiring local anesthesia, dosage should be limited and the anesthetic administered only in facilities equipped for handling possible emergencies.

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