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CURRENT ISSUEITALIAN JOURNAL OF MAXILLOFACIAL SURGERY

A Journal on Maxillofacial Surgery

Official Journal of the Italian Society of Maxillofacial Surgery

Frequency: 3 issues

ISSN 1120-7558

Online ISSN 1827-1901

 

Rivista Italiana di Chirurgia Maxillo-Facciale 2002 December;13(3):155-61

    ORIGINAL ARTICLES

Fibrin glue and platelet-rich plasma in maxillo-facial surgery. Preparation method and clinical and radiological TC follow-up

Cortese A., Saturno M., Savastano G.

Department of Maxillo-Facial Surgery Federico II University, Naples, Italy

Aim. This ­research ­aimed to eval­u­ate a meth­od ­for ­the pro­duc­tion of ­fibrin ­glue (FG) ­and plate­let-­rich plas­ma (­PRP) devel­oped by ­the Immunohaematology ­and Transfusion Service, Federico II University, Naples. The ­results of employ­ing FG ­and ­PRP dur­ing recon­struc­tive sur­gery ­for ­bone aug­men­ta­tion ­were eval­u­at­ed.
Methods. Twelve ­patients pro­grammed ­for ­bone aug­men­ta­tion sur­gery ­were sub­di­vid­ed ­into 2 ­groups of ­6 ­patients, ­each con­tain­ing ­four ­patients oper­at­ed ­4 ­major ­sinus ­lift ­and ­2 by autol­o­gous cal­var­ia ­graft. Patients in Group I under­went sur­gery with­out FG ­and ­PRP where­as ­those in Group II ­received FG ­and ­PRP; 300 ml of ­blood ­were with­drawn ­from ­each ­patient in Group II ­for prep­ar­a­tion of FG ­and ­PRP.
Results. Mean fibrino­gen con­cen­tra­tion in FG ­was 1100-1200 mg/dl. Mean con­cen­tra­tion in ­PRP ­was 1×109±0.5. Concentration ­was ­increased by 415.7% ­for FG ­and 380, 228% ­for ­PRP. Bone resorp­tion of ­grafts at ­1 ­year ­was 10% ­less in ­sinus ­lift oper­a­tions ­using FG ­and ­PRP ­and 15% ­less in cal­var­ia ­bone ­grafts ­using FG ­and ­PRP.
Conclusion. The ­results ­show ­that ­this ­safe, ster­ile, rap­id ­and ­cheap prep­ar­a­tion meth­od ­for FG ­and ­PRP ­improves ­bone ­graft sur­vi­val ­and reduc­es infec­tion ­rate.

language: English


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