Advanced Search

Home > Journals > The Journal of Cardiovascular Surgery > Past Issues > Articles online first > The Journal of Cardiovascular Surgery 2015 Sep 08



A Journal on Cardiac, Vascular and Thoracic Surgery

Indexed/Abstracted in: BIOSIS Previews, Current Contents/Clinical Medicine, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,632

Frequency: Bi-Monthly

ISSN 0021-9509

Online ISSN 1827-191X


The Journal of Cardiovascular Surgery 2015 Sep 08

Short- and mid-term results after Transapical Transcatheter Aortic Valve Replacement in nonagenarians

de Biasi A. R. 1, Wong S. C. 2, Minutello R. M. 2, Voudris K. 2, Worku B. 1, Girardi L. N. 1, Salemi A. 1

1 Department of Cardiothoracic Surgery, Weill Cornell Medical College / New York-Presbyterian Hospital, New York, NY, USA;
2 Department of Medicine, Weill Cornell Medical College / New York-Presbyterian Hospital, New York, NY, USA

AIM: Recent reports have suggested that advanced age may preclude favorable outcomes in transcatheter aortic valve replacement (TAVR), particularly when performed via transapical (TA) access. However, detailed examinations of TA-TAVR in nonagenarian patients are lacking in the contemporary literature. We therefore describe our experience with 25 consecutive nonagenarians who underwent TA-TAVR and report their short- and mid-term outcomes.
METHODS: We identified all patients 90 years old or greater who underwent TA-TAVR between 2009-2014 at our institution. Demographic, comorbidity and echocardiographic data were obtained for all patients as were their in-hospital, 30-day, and 1-year outcomes. Overall survival was calculated using the Kaplan-Meier method.
RESULTS: The mean Society of Thoracic Surgeons’ predicted risk of mortality was 10.2 (SD ± 3.4) %. Twenty-four nonagenarians received TA-TAVR secondary to severe aortic stenosis while 1 had a valve-in-valve procedure for a regurgitant bioprosthetic valve. There were no conversions to open surgery, no aborted procedures, and no in-hospital deaths or strokes; 44% of patients (N = 11) were discharged to home. Five patients required cardiac rehospitalization within the first 30 days and 2 experienced strokes during the first year. Overall 30-day and 1- year survival were 100% and 83%, respectively.
CONCLUSION: TA-TAVR can safely be performed on nonagenarians subjected to otherwise standard selection criteria. Chronology should not stand as a routine contraindication to this procedure; rather, comorbidities and functional status should define patient eligibility for TA- TAVR.

language: English


top of page