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THE JOURNAL OF CARDIOVASCULAR SURGERY

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The Journal of Cardiovascular Surgery 2015 June;56(3):401-7

Copyright © 2015 EDIZIONI MINERVA MEDICA

language: English

The pros and cons of endovascular and open surgical treatments for patients with acute limb ischemia

Branco B. C. 1, Montero-Baker M. F. 2, Mills Sr. J. L. 2

1 Department of Surgery, University of Arizona, Tucson, AZ, USA;
2 Division of Vascular and Endovascular Surgery, University of Arizona, Tucson, AZ, USA


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The present review addresses the pros and cons of the current, wide variety of therapeutic options available for the treatment of acute limb ischemia (ALI). Despite five prospective randomized controlled trials comparing catheter directed thrombolysis and open surgical revascularization, no single treatment strategy can yet be considered optimal for patients with ALI. This report includes 20 years of published data to evaluate the efficacy and safety profile of thrombolytic agents and adjunctive endovascular techniques when compared to open surgical revascularization.

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jmills@u.arizona.edu