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Indexed/Abstracted in: BIOSIS Previews, Current Contents/Clinical Medicine, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,632
ACUTE LOWER EXTREMITY ISCHEMIA
Branco B. C. 1, Montero-Baker M. F. 2, Mills Sr. J. L. 2
1 Department of Surgery, University of Arizona, Tucson, AZ, USA;
2 Division of Vascular and Endovascular Surgery, University of Arizona, Tucson, AZ, USA
The present review addresses the pros and cons of the current, wide variety of therapeutic options available for the treatment of acute limb ischemia (ALI). Despite five prospective randomized controlled trials comparing catheter directed thrombolysis and open surgical revascularization, no single treatment strategy can yet be considered optimal for patients with ALI. This report includes 20 years of published data to evaluate the efficacy and safety profile of thrombolytic agents and adjunctive endovascular techniques when compared to open surgical revascularization.