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THE JOURNAL OF CARDIOVASCULAR SURGERY

A Journal on Cardiac, Vascular and Thoracic Surgery


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  LATEST DEVELOPMENTS IN THE TREATMENT OF CRITICAL LIMB ISCHEMIA


The Journal of Cardiovascular Surgery 2014 October;55(5):625-30

language: English

Drug-coated balloons and drug-eluting stents: clinical effectiveness revisited

Fanelli F., Cannavale A.

Vascular and Interventional Radiology Unit, Department of Radiological Sciences, La Sapienza University of Rome, Rome, Italy


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Critical limb ischemia (CLI) is a common and devastating manifestation of peripheral arterial disease leading to ischemic rest pain, ulcerations, gangrene and tissue loss. Thus advanced endovascular techniques have been developed in order to achieve higher success rate, such as retrograde recanalisation and drug eluting devices. However, the correlation between patency of the vessels and clinical outcome (limb salvage, ulcer healing, Rutherford class improvement) is still debated. We reviewed the most recent trials and studies investigating the clinical effectiveness of drug eluting stents and balloons for the treatment of CLI.

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fabrizio.fanelli@uniroma1.it