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Schoenhoff F., Schmidli J., Czerny M., Carrel T. P.
Department of Cardiovascular Surgery, University Hospital Berne, Berne, Switzerland
Acute dissection and rupture of aortic aneurysms comprise for 1-2% of all deaths in developed countries. Dilation of the aorta is caused by several different mechanisms including inherited disorders of connective tissue. Recent reports estimate that 20% of patients presenting with thoracic aortic disease do have an underlying genetic basis of disease.