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THE JOURNAL OF CARDIOVASCULAR SURGERY

A Journal on Cardiac, Vascular and Thoracic Surgery


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  NEW RESULTS IN THE ENDOVASCULAR MANAGEMENT OF ABDOMINAL AORTIC ANEURYSMS (AAAs) (PART II)


The Journal of Cardiovascular Surgery 2012 October;53(5):579-94

Copyright © 2012 EDIZIONI MINERVA MEDICA

language: English

The use of Endurant stent-graft for abdominal aortic aneurysm: the story about extension of Instruction for Use with persistent good results of stent-graft latest generation

Rancic Z. 1, Pecoraro F. 2, Pfammatter T. 3, Banzic I. 1, Klein H. 1, Kyriakidis K. 4, Mayer D. 1, Lachat M. 1

1 Clinic for Cardiovascular Surgery, University Hospital Zurich, Zurich, Switzerland; 2 Vascular Surgery Unit, University of Palermo, Palermo, Italy; 3 Interventional and Diagnostic Radiology, University Hospital Zurich, Zurich, Switzerland; 4 Department of Vascular Surgery, Konstantopouleio General Hospital “AgiaOlga”, Athens, Greece


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The Endurant stent-graft (Medtronic, Inc., Minneapolis, MN, USA) is a latest generation device for the treatment of abdominal aortic aneurysm. The idea behind designing such a graft came from the intention to broad the instruction for use (IFU) and to enable it to treat more challenging anatomy including the 10mm neck lengths, and more severe suprarenal and infrarenal angulations. Endurant stent-graft has active fixation through suprarenal stent with anchoring pins to provide migration resistance, optimized heights of stents and spacing between them for improved flexibility and conformability, low-profile delivery system with hydrophilic coating and controlled simple deployment mechanism. Short term results are excellent. Technical and clinical success is confirmed in Regulatory trials (EU and USA), as well as in ENGAGE and the Canadian registry. Many current publications record the use of Endurant stent-graft outside the Instruction for use. The results in a group of patients outside the instruction for use are comparable to those within instruction for use; with the exception of perioperative proximal endoleak type I. Mid-term results are consistent with short-term results. The long-term results are lacking.

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Zoran.rancic@usz.ch