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THE JOURNAL OF CARDIOVASCULAR SURGERY

A Journal on Cardiac, Vascular and Thoracic Surgery


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REVIEWS  AN UPDATE ON AVAILABLE STENTS FOR THE MANAGEMENT OF ABDOMINAL AORTIC ANEURYSMS


The Journal of Cardiovascular Surgery 2009 April;50(2):165-70

language: English

Zenith® abdominal aortic aneurysm endovascular graft: a literature review

D’Elia P. 1, Tyrrell M. 2, Azzaoui R. 1, Sobocinski J. 1, Koussa M. 1, Valenti D. 2, Haulon S. 1

1 Vascular Surgery, Cardiology Hospital CHRU de Lille, Lille, France
2 Vascular Surgery, King’s College Hospital London, United Kingdom


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The early experience of endovascular aneurysm repair (EVAR) using “first generation” devices was disappointing. There was an appreciable incidence of delayed, post-EVAR, aneurysm rupture. This was primarily a consequence of structural device failure. These failures provided important lessons for re-design and the modern “second generation” devices, including the Zenith® (Cook Inc, Bloomington, IN, USA) endograft, are thought to be more reliable, particularly providing better fixation and sealing and also a more durable stent/fabric structure. This article comprises a review of the English literature detailing the endovascular treatment of abdominal aortic aneurysms using the Zenith® endograft. It focuses on clinical studies or trials with intermediate to long-term follow-up, and related the literature to our own experience. In the series examined (N.=2 017 patients) the early mortality rate ranged from 0% to 4.1% and the technical success rate from 97.7% to 100%. The re-intervention rate was related to the length of follow-up (6.8% to 14%). Conversion rates were consistently <1%. There was a low incidence of device migration, limb thrombosis, component separation and stent fracture. These data support the ongoing use of the Zenith® endovascular graft in patients with abdominal aortic aneurysms suitable for EVAR.

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