Advanced Search

Home > Journals > The Journal of Cardiovascular Surgery > Past Issues > The Journal of Cardiovascular Surgery 2009 February;50(1) > The Journal of Cardiovascular Surgery 2009 February;50(1):109-21



A Journal on Cardiac, Vascular and Thoracic Surgery

Indexed/Abstracted in: BIOSIS Previews, Current Contents/Clinical Medicine, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,632

Frequency: Bi-Monthly

ISSN 0021-9509

Online ISSN 1827-191X


The Journal of Cardiovascular Surgery 2009 February;50(1):109-21

Peripheral arterial disease and concomitant coronary artery disease 


Prognosis of patients with peripheral arterial disease

Welten G. M. J. M. 1, Schoutern O. 1, Chonchol M. 2, Hoeks S. E. 3, Bax J. J. 4, Van Domburg R. T. 3, Poldermans D. 5

1 Department of Vascular Surgery Erasmus Medical Centre, Rotterdam, The Netherlands
2 Division of Renal Diseases and Hypertension University of Colorado Health Sciences Centre Denver, CO, USA
3 Department of Cardiology Erasmus Medical Centre Rotterdam, The Netherlands
4 Department of Cardiology Leiden Medical Centre, Leiden, The Netherlands
5 Department of Anesthesiology Erasmus Medical Centre, Rotterdam, The Netherlands

The incidence of peripheral arterial disease (PAD) is on the increase and is associated with a major health concern in current practical care. The most common disease process underlying PAD is atherosclerosis. Atheroscle-rosis is a complex generalized disease affecting several arterial beds, including the peripheral and coronary circulation. Especially in patients with PAD, high incidences of coronary artery disease (CAD) have been observed, which may be asymptomatic or symptomatic. The prognosis of patients with PAD is related to the presence and extent of underlying CAD. In patients with PAD undergoing major vascular surgery, cardiac complications are the major cause of perioperative morbidity and mortality and indicate a high-risk for adverse long-term cardiac outcome. In order to improve outcome for PAD patients, assessment and aggressive therapy of atherosclerotic risk factors and usage of cardio-protective medications is recommended. Unfortunately, substantial differences in risk factor management and treatment and long-term outcome have been reported between PAD and CAD patients.

language: English


top of page