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THE JOURNAL OF CARDIOVASCULAR SURGERY
A Journal on Cardiac, Vascular and Thoracic Surgery
Indexed/Abstracted in: BIOSIS Previews, Current Contents/Clinical Medicine, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,632
CASE REPORTS THORACIC SECTION
The Journal of Cardiovascular Surgery 2002 August;43(4):559-61
Severe hypoglycaemia associated with a giant solitary fibrous tumor of the pleura
Filosso P. L., Oliaro A., Rena O., Papalia E., Ruffini E., Mancuso M.
Department of Thoracic Surgery, University of Torino, San Giovanni Battista Hospital, Torino, Italy
Solitary fibrous tumors (SFT) of the pleura are a rare neoplasm, with benign biological behaviour. Recurrences are rare, and no distant metastases are described in the literature. SFT can secrete hormone-like substances, responsible for paraneoplastic syndromes. The authors describe a case of severe hypoglycaemia due to insulin-like growth factor II (IGF-2)’s secretion by a giant SFT of the pleura. Hypoglycaemia was controlled by the resection of the tumor. Diagnosis and surgical management of these neoplasms are also discussed.