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THE JOURNAL OF CARDIOVASCULAR SURGERY

A Journal on Cardiac, Vascular and Thoracic Surgery


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The Journal of Cardiovascular Surgery 2002 August;43(4):559-61

language: English

Severe hypoglycaemia associated with a giant solitary fibrous tumor of the pleura

Filosso P. L., Oliaro A., Rena O., Papalia E., Ruffini E., Mancuso M.

Depart­ment of Tho­racic Sur­gery, Uni­ver­sity of ­Torino, San Gio­vanni Bat­tista Hos­pital, ­Torino, ­Italy


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Sol­i­tary ­fibrous ­tumors (SFT) of the ­pleura are a ­rare neo­plasm, ­with ­benign bio­log­ical beha­viour. Recur­rences are ­rare, and no dis­tant metas­tases are ­described in the lit­er­a­ture. SFT can ­secrete hor­mone-­like sub­stances, respon­sible for par­a­neo­plastic syn­dromes. The ­authors ­describe a ­case of ­severe hypo­gly­caemia due to ­insulin-­like ­growth ­factor II (IGF-2)’s secre­tion by a ­giant SFT of the ­pleura. Hypo­gly­caemia was con­trolled by the resec­tion of the ­tumor. Diag­nosis and sur­gical man­age­ment of ­these neo­plasms are ­also dis­cussed.

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