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THE JOURNAL OF CARDIOVASCULAR SURGERY

A Journal on Cardiac, Vascular and Thoracic Surgery


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REVIEW ARTICLES  VASCULAR SECTION


The Journal of Cardiovascular Surgery 2002 June;43(3):349-57

language: English

Vascular restenosis. Basic science and clinical implications

Heckenkamp J., Gawenda M., Brunkwall J.

From the Depart­ment of Sur­gery Divi­sion of Vas­cular Sur­gery Uni­ver­sity of ­Cologne, ­Cologne, Ger­many


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Car­di­o­vas­cular inter­ven­tions to cor­rect arte­rial occlu­sive dis­ease ­have excel­lent ­short-­term ­results, but ­long-­term ­patency is ­still seri­ously com­pro­mised by the devel­op­ment of resten­osis. ­This ­review ­will pro­vide a por­trait of the mech­a­nisms fol­lowing vas­cular ­injury, ­define the clin­ical ­scope of the ­problem and out­line devel­op­ments of dif­ferent ther­a­peu­tical strat­e­gies to pre­vent resten­osis.

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