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Indexed/Abstracted in: BIOSIS Previews, Current Contents/Clinical Medicine, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,632
Online ISSN 1827-191X
Rigatelli G. L., Carraro U. *, Barbiero M., Zanchetta M. **, Rigatelli G.
From the Division of Cardiology Interventional Cardiology LAB and Cardiomyoplasty Project Unit Legnago General Hospital, Verona, Italy
*Department of Biomedical Sciences University of Padua, Padua, Italy
**Division of Cardiology Cittadella General Hospital, Padua, Italy
Background. There are no data regarding real cardiac assistance in demand dynamic cardiomyoplasty (DDCMP). A test of the use of Doppler flow wire is presented to demonstrate cardiac assistance in DDCMP.
Methods. Comparative study in hospitalized care. A peripheral FlexTM Doppler flow wire of 0.018 inch was advanced through a 4F introducer femoral arterial in seven DDCMP patients (age=57.1±6.2 years; NYHA= 1.4±0.5). A short period of 10 sec with stimulator off and a following period of 15 sec with clinical stimulation were recorded. We measured the maximum peak aortic flow velocity (MPAV) in all beats. Latissimus dorsi (LD) mechanogram was simultaneously recorded.
Results. Statistical analysis showed an increase not only in MPAV in assisted period versus rest, but also in assisted beats versus unassisted (8.42±6.98% and 7.55±3.07%).
Conclusions. Intravascular Doppler proved real systolic assistance in DDCMP; in DDCMP systolic assistance is correlated to the LD wrap speed of contraction, suggesting that demand stimulation could be the most effective protocol in dynamic cardiomyoplasty.