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CURRENT ISSUETHE JOURNAL OF CARDIOVASCULAR SURGERY

A Journal on Cardiac, Vascular and Thoracic Surgery

Indexed/Abstracted in: BIOSIS Previews, Current Contents/Clinical Medicine, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,632

Frequency: Bi-Monthly

ISSN 0021-9509

Online ISSN 1827-191X

 

The Journal of Cardiovascular Surgery 2001 October;42(5):611-4

CARDIAC SECTION 

    ORIGINAL ARTICLES

Right vagal nerve stimulation for coronary anastomosis without cardiopulmonary bypass. Investigation in dogs

Hayashi I., Yamamoto T., Hosoda Y.

From the Depart­ment of Tho­racic and Car­di­o­vas­cular Sur­gery, Jun­tedo Uni­ver­sity, ­Tokyo, ­Japan

Back­ground. The pur­pose of ­this ­study is to ­assess the poten­tial of ­right ­vagal ­nerve stim­u­la­tion for ­reducing the ­heart ­rate ­during cor­o­nary anas­tom­osis ­without car­di­o­pul­mo­nary ­bypass.
­Methods. ­Through the ­fourth ­left inter­costal ­space, ­left ­internal tho­racic ­artery ­grafts ­were ­sutured to the ­left ante­rior ­descending ­artery ­with the ­heart ­beating. In ­Group I (n=7), two ­dogs under­went ­right cer­vical ­vagal stim­u­la­tion ­alone and ­five ­dogs under­went ­right cer­vical ­vagal stim­u­la­tion ­during intra­ve­nous infu­sion of dil­tiazem or verap­amil. In ­Group II (n=3), one dog under­went ­right tho­racic ­vagal stim­u­la­tion ­alone and two ­dogs under­went ­right tho­racic ­vagal stim­u­la­tion ­during intra­ve­nous infu­sion of dil­tiazem or verap­amil. The tho­racic ­vagal ­nerve was iso­lated endo­scop­i­cally. The elec­tro­car­di­o­gram and ­aortic pres­sure ­were mon­i­tored ­during inter­ven­tions.
­Results. In ­Group I, cer­vical ­vagal stim­u­la­tion ­reduced the ­heart ­rate ­from 190 to 45 and 180 to 42 b/min. ­During intra­ve­nous infu­sion of dil­tiazem or verap­amil, cer­vical ­vagal stim­u­la­tion ­caused ven­tric­ular ­arrest. In ­Group II, tho­racic ­vagal stim­u­la­tion ­decreased the ­heart ­rate ­from 205 to 70 ­b/min, and stim­u­la­tion ­during intra­ve­nous infu­sion of dil­tiazem ­caused ven­tric­ular ­arrest.
Con­clu­sions. ­Right ­vagal stim­u­la­tion ­during intra­ve­nous infu­sion of dil­tiazem or verap­amil has poten­tial ­value as a tech­nique for ­reducing the ­heart ­rate ­during cor­o­nary anas­tom­osis ­without car­di­o­pul­mo­nary ­bypass.

language: English


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