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THE JOURNAL OF CARDIOVASCULAR SURGERY

A Journal on Cardiac, Vascular and Thoracic Surgery


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The Journal of Cardiovascular Surgery 2001 June;42(3):345-8

language: English

Recurrent cardiac myxoma: why it occurs. A case report with literature review

Reber D., Birnbaum D. E.

From the Depart­ment of Car­di­oth­o­racic Sur­gery Uni­ver­sity Hos­pital, Ren­gens­burg, Ger­many


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Two ­years ­after sur­gical ­removal of a ­right ­atrial ­myxoma, recur­rences ­were ­found in ­both ­atria: mul­tiple ­tumors in the ­right ­atrium and one ­tumor in the ­left ­atrium. All ­were sub­se­quently ­removed. ­There was no fur­ther recur­rence ­during the fol­lowing 3 ­years. We ­report on an ­unusual ­case ­which, to our knowl­edge, is the ­first ­time ­that ­such a ­case ­appears in the lit­er­a­ture. We ­also dis­cuss the clin­ical symp­toms, diag­nostic ­aspects, as ­well as ­details of a lit­er­a­ture ­review ­regarding recur­ring ­myxoma. We ­think the recur­rence in our ­case was due to totip­o­tent mul­ti­cen­tricity of the ­tumor. Pre­vious ­studies ­showed ­that the recur­rence ­might be due to the fol­lowing rea­sons: inad­e­quate resec­tion, or mul­ti­focal pat­tern beha­viour of a ­benign ­myxoma, ­either in the ­same or in a dif­ferent loca­tion as the pri­mary ­tumor. ­Familial dis­po­si­tion may ­also ­play a ­role in recur­rent devel­op­ment. The ­abnormal DNA ­ploidy pat­tern of ­myxoma ­patients ­showed a ­high recur­rence.

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