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CURRENT ISSUETHE JOURNAL OF CARDIOVASCULAR SURGERY

A Journal on Cardiac, Vascular and Thoracic Surgery

Indexed/Abstracted in: BIOSIS Previews, Current Contents/Clinical Medicine, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,632

Frequency: Bi-Monthly

ISSN 0021-9509

Online ISSN 1827-191X

 

The Journal of Cardiovascular Surgery 2001 June;42(3):317-22

CARDIAC SECTION 

    ORIGINAL ARTICLES

Aortic valve replacement with the composite LabcorTM porcine bioprosthesis in the elderly

Pavie A. J., Nzomvuama A. N., Bonnet N., Bors V. H., Gandjbakhch I.

From the Tho­racic and Car­di­o­vas­cular Sur­gery Depart­ment Hôpital ''La ­Pitié-­Salpétrière'', ­Paris, ­France

Back­ground. ­This ­paper ­presents the anal­ysis of clin­ical ­results of the com­posite por­cine ­Labcor™ bio­pros­thesis in the replace­ment of ­aortic ­valves in the eld­erly.
­Methods. ­This ret­ro­spec­tive ­study was car­ried out in the Tho­racic and Car­di­o­vas­cular Sur­gical Depart­ment, La ­Pitié-­Salpétrière Hos­pital, ­Paris, for replace­ment of cal­ci­fied, ste­nosed ­aortic ­valves ­between 1988 and 1995. It ­involved a ­series of 100 ­patients ­aged 70 and ­over (mean: 80±5 ­years ­ranging ­from 70 to 90). ­There ­were 63 ­female and 37 ­male ­patients. Pre­op­er­a­tively, ­five ­patients ­were in ­NYHA ­Class I, 23 in ­Class II, 65 in ­Class III and 7 in ­Class IV.
­Results. Fif­teen ­patients ­died in the ­early post­op­er­a­tive ­stage and 13 ­during the ­follow-up ­period. ­There was no evi­dence of ­valve ­failure. The ­average ­follow-up was 32 ­months and the actu­arial sur­vival ­rate at 5 ­years was 74±5%. Com­pli­ca­tions due to ­bleeding ­occurred in 3 ­patients ­taking anti­co­ag­u­lant treat­ment. ­There ­were nei­ther val­vular throm­bosis nor embo­lism. Two ­patients pre­sented ­with pros­thetic endo­car­ditis. Two ­patients ­received a reop­er­a­tion ­because of ­leakage (1 ­septic). The ­five-­year ­follow-up ­showed ­that 96% of ­patients did not ­require fur­ther sur­gery. ­When ­this ­study was com­pleted, 83% of ­patients ­were in ­Class I or II ­versus 71% in ­Class III or IV ­prior to sur­gery.
Con­clu­sions. In the ­early/­middle ­follow-up ­term, the ­results ­obtained ­when ­replacing the ­aortic ­valve ­with the com­posite ­Labcor™ bio­pros­thesis in the eld­erly are sat­is­fying. Nev­er­the­less, fur­ther ­long-­term assess­ment is ­needed.

language: English


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