Home > Journals > The Journal of Cardiovascular Surgery > Past Issues > The Journal of Cardiovascular Surgery 2001 February;42(1) > The Journal of Cardiovascular Surgery 2001 February;42(1):125-9

CURRENT ISSUE
 

ARTICLE TOOLS

Reprints

THE JOURNAL OF CARDIOVASCULAR SURGERY

A Journal on Cardiac, Vascular and Thoracic Surgery


Indexed/Abstracted in: BIOSIS Previews, Current Contents/Clinical Medicine, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 2,179


eTOC

 

ORIGINAL ARTICLES  THORACIC PAPERS


The Journal of Cardiovascular Surgery 2001 February;42(1):125-9

Copyright © 2009 EDIZIONI MINERVA MEDICA

language: English

Experience with fatal interstitial pneumonia after operation for lung cancer

Tanita T., Chida M., Hoshikawa Y., Handa M., Sato M., Sagawa M., Ono S., Matsumura Y., Kondo T., Fujimura S.

From the Department of Thoracic Surgery Institute of Development, Aging and Cancer Tohoku University, Sendai, Japan *Department of Surgery, Sendai Kousei Hospital, Sendai, Japan


PDF  


Background. The num­ber of ­patients ­with ­lung can­cer is increas­ing. This ­study was under­tak­en to real­ize the prob­abil­ity, ­fate and man­age­ment of ­acute ­fatal post­op­er­a­tive com­pli­ca­tions. Since inter­sti­tial pneu­mo­nia was one of the ­most ­fatal post­op­er­a­tive com­pli­ca­tions, to ­know its inci­dence and ­fate is ­very impor­tant.
Methods. A ­total of 2667 ­patients who under­went thor­a­cot­o­my ­caused by malig­nant ­tumors dur­ing the ­past 17 ­years ­were ­reviewed and stud­ied. We per­formed inves­ti­ga­tions on med­i­cal ­records, ­chest X-­rays, ­whole-­body CT ­films, oper­a­tive ­records and path­o­log­i­cal spec­i­mens for all inpa­tients.
Results. Nineteen ­patients ­died in hos­pi­tal 30 ­days ­after thor­a­cot­o­my (oper­a­tive ­death). Nine ­patients ­died in hos­pi­tal ­more ­than 31 ­days ­after thor­a­cot­o­my (hos­pi­tal ­death). Eight cas­es out of 28 ­patients (oper­a­tive and hos­pi­tal ­deaths) devel­oped and final­ly ­died by inter­sti­tial pneu­mo­nia. Each ­case was treat­ed ­with ster­oids, neu­troph­il-elas­tase inhib­i­tor, and/or immu­no­sup­pres­sive ­agents. These ­patients ­could not be select­ed by any pre­op­er­a­tive labor­a­to­ry exam­ina­tion, ­such as pre­op­er­a­tive pul­mo­nary func­tion ­tests, ser­um bio­chem­is­try ­tests, and ­chest X-ray or CT ­films. Interstitial pneu­mo­nia as a com­pli­ca­tion of post­op­er­a­tive ­stage, was ­fatal and ­once devel­oped, it was ­very dif­fi­cult to ­save ­their ­lives.
Conclusions. Since we report­ed the cas­es who ­died from a­cute post­op­er­a­tive com­pli­ca­tions, espe­cial­ly inter­sti­tial pneu­mo­nia, we ­could not ­present effec­tive man­age­ment. However, in ­this ­report, sev­er­al ther­a­peu­tic ­trials ­that may ­solve the prob­lems of ­acute post­op­er­a­tive inter­sti­tial pneu­mo­nia ­were pro­posed.

top of page

Publication History

Cite this article as

Corresponding author e-mail