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THE JOURNAL OF CARDIOVASCULAR SURGERY
A Journal on Cardiac, Vascular and Thoracic Surgery
Indexed/Abstracted in: BIOSIS Previews, Current Contents/Clinical Medicine, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,632
CASE REPORTS THORACIC PAPERS
The Journal of Cardiovascular Surgery 1999 December;40(6):893-5
Extended thymectomy for myasthenia gravis in an octogenarian. A case report
Hamada Y., Sakai Y., Ito H., Ichikawa H., Morishita Y.
From the Department of Chest Surgery Department of Neurology and Department of Pathology Maebashi Red Cross Hospital and Second Department of Surgery
Gunma University School of Medicine, Maebashi, Japan
An 86-year-old woman with myasthenia gravis successfully underwent an extended thymectomy. The patient had a 2-year history of generalized myasthenia and had limited response to anticholinesterases and steroids. An extended thymectomy was successfully performed in the usual fashion. The postoperative course was uneventful except for an episode of psychosis probably due to postoperative steroid therapy. The steroid dosage was gradually reduced to 5 mg/day over seven months after the operation, during which she became fully asymptomatic. No symptoms due to myasthenia have surfaced for over 2 years after surgery. Although elderly patients are usually considered to be less responsive to an operation, thymectomy may sometimes be the treatment of choice for myasthenia gravis even in octogenarians.