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THE JOURNAL OF CARDIOVASCULAR SURGERY
A Journal on Cardiac, Vascular and Thoracic Surgery
Indexed/Abstracted in: BIOSIS Previews, Current Contents/Clinical Medicine, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,632
CASE REPORTS VASCULAR PAPERS
The Journal of Cardiovascular Surgery 1999 April;40(2):261-4
Primary antiphospholipid syndrome: a cause of catastrophic shunt thrombosis in the newborn
Deally C., Hancock B. J., Giddins N., Hawkins L., Odim J.
From the Children’s Heart Center Winnipeg, Manitoba, USA
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This is a unique report of systemic-to-pulmonary artery shunt thromboses secondary to primary antiphospholipid syndrome and antithrombin III deficiency in a neonate with cyanotic congenital heart disease. This infant with tricuspid atresia experienced thromboses of two modified Blalock-Taussig shunts en route to a bi-directional cavo-pulmonary shunt and potential future Fontan operation. Chronic warfarin anticoagulation has prevented additional thrombo-embolic events.