Advanced Search

Home > Journals > The Journal of Cardiovascular Surgery > Past Issues > The Journal of Cardiovascular Surgery 1998 June;39(3) > The Journal of Cardiovascular Surgery 1998 June;39(3):363-6

ISSUES AND ARTICLES   MOST READ   eTOC

CURRENT ISSUETHE JOURNAL OF CARDIOVASCULAR SURGERY

A Journal on Cardiac, Vascular and Thoracic Surgery


Indexed/Abstracted in: BIOSIS Previews, Current Contents/Clinical Medicine, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,632

 

The Journal of Cardiovascular Surgery 1998 June;39(3):363-6

CARDIAC PAPERS 

 TECHNICAL NOTES

Right and ­left ven­tric­ular inter­ac­tion in ven­tric­ular fib­ril­la­tion ­with mechan­ical main­te­nance of the cir­cu­la­tion

Charitos Ch. E., Nanas J. N., Nanas S. N., Chatzigeorgiou I., Alevizakos N., Cosmas K., Moulopoulos S. D.

From the Depart­ment of Clin­ical Ther­a­peu­tics Uni­ver­sity of ­Athens, Med­ical ­School, ­Athens, ­Greece

Objec­tive. To inves­ti­gate the pos­sible mech­a­nisms of ­right and ­left ven­tric­ular inter­ac­tion ­during ven­tric­ular fib­ril­la­tion (VF) ­with mechan­ical main­te­nance of the cir­cu­la­tion.
Experi­mental ­design. In ­this experi­mental ­study, two ­para-­aortic coun­ter­pul­sa­tion ­devices (­PACDs) ­were ­implanted in 14 mon­grel ­dogs.
Set­ting. The ­PACD is a ­spheroid, valve­less, ­with one ­opening, 100 ml ­stroke ­volume ­assisting ­device. ­After mid­ster­notomy and per­i­car­di­otomy, two ­PACDs ­were ­implanted on the ­ascending ­aorta and the pul­mo­nary ­artery, respec­tively. Cath­e­ters ­were ­placed ­into the ­aortic ­arch, and the ­left and ­right ven­tri­cles. An elec­tro­mag­netic ­probe was ­placed on the ­descending ­aorta.
Inter­ven­tions. ­After the com­ple­tion of the experi­mental prep­ar­a­tion, VF was ­induced and the two ­devices ­were syn­chron­ized and ­pumped simul­ta­ne­ously for 10 min­utes (A). Sub­se­quently, the ­left ­sided ­PACD ­pumped ­alone for the ­same ­period of ­time (B). ­This ­sequence was ­repeated 1-10 ­times in ­each experi­ment.
Meas­ures. The ­aortic pres­sures, the ­left and ­right ven­tric­ular pres­sures and the car­diac ­index ­were ­obtained at the end of ­each inter­ven­tion.
­Results. The simul­ta­neous ­pumping of the two ­devices (A) com­pared ­with the ­pumping of ­that ­implanted on the ­ascending ­aorta (B) ­resulted in: ­higher ­peak ­aortic pres­sure 119.1±32.1 ­mmHg (A) vs 105.7±36.4 ­mmHg (B), p<0.001, ­mean ­aortic pres­sure 42.1±13.2 ­mmHg vs 27.8±10.5 ­mmHg, p<0.001, ­mean ­left ven­tric­ular pres­sure 18.4+4.0 ­mmHg vs 11.7±3.6 ­mmHg, p<0.001, and car­diac ­index 105.7±40.1 ml/kg/min vs 82.0±39.9 ml/kg/mm, p<0.001, and ­lower ­right ven­tric­ular pres­sure 10.1±3.2 ­mmHg vs 13.3±2.6 ­mmHg, p<0.001.
Con­clu­sions. Main­te­nance of the cir­cu­la­tion ­during VF ­with the ­PACD ­implanted on the ­ascending ­aorta ­results in equal­iza­tion of the ­right and ­left ven­tric­ular pres­sures. In con­trast, ­when ­both ­devices are ­pumping simul­ta­ne­ously, the ­left ven­tric­ular pres­sure is sig­nif­i­cantly ­higher ­than the ­right one and the assis­tance is ­more effec­tive.

language: English


FULL TEXT  REPRINTS

top of page