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A Journal on Physiopathology and Therapy of Chronic Cutaneous Ulcers
Official Journal of the Italian Association for Cutaneous Ulcers
Indexed/Abstracted in: EMBASE, Scopus, Emerging Sources Citation Index
Acta Vulnologica 2016 March;14(1):40-3
Epidemiology of antibiotic resistance and MBL genes among Pseudomonas aeruginosa and Acinetobacter baumannii clinical strains isolated from burnt patients in Iran: a systematic review
Ali HASHEMI, Samira TARASHI, Soroor ERFANIMANESH
Department of Microbiology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
INTRODUCTION: Pseudomonas aeruginosa and Acinetobacter baumannii are common gram-negative non-fermenter opportunistic bacteria associated with nosocomial infections, especially among hospitalized burn patients.
EVIDENCE ACQUISITION: In this study, PubMed was searched using the following keywords: “P. aeruginosa”, “A. baumannii”, “metallo-β-lactamases”, “burn or burnt”, “Iran”, “MBL”, “VIM-1 gene”, “IMP-1 gene” and “NDM-1 gene”. Fifteen articles were eligible to be included in our systematic review.
EVIDENCE SYNTHESIS: These studies were carried out in Tehran, Tabriz, Kurdistan and Ahvaz. Number of imipenem resistant strains reported of burnt patients and metallo-beta-lactamases producing isolates reported of burnt patients in Iran. Among MBL genes, blaVIM is more than blaIMP and blaNDM genes in Iran.
CONCLUSIONS: The prevalence of ß-lactamase-producing isolates, and their isolation from life-threatening infections, is increasing worldwide at an alarming rate.