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A Journal on Physiopathology and Therapy of Chronic Cutaneous Ulcers

Official Journal of the Italian Association for Cutaneous Ulcers
Indexed/Abstracted in: EMBASE, Scopus, Emerging Sources Citation Index




Acta Vulnologica 2015 September;13(3):157-70

language: English, Italian

Modalities of tissue repair and wound treatment

Paggi B., Dini V., Romanelli M.

Dermatology Clinic, Department of Clinic and Experimental Medicine, University of Pisa, Pisa, Italy


New treatments for chronic wounds have led to improvements in lesion management and in the quality of assistance provided by medical and paramedical staff, but lesion monitoring methodologies have not kept pace with this progress. The constant improvement of diagnostic and therapeutic procedures, together with the increase of life lasting, results in a higher frequency of patients suffering from chronic cutaneous ulcers. As these pathologies imply high-cost treatments and often poor outcomes in terms of quality of life, a decrease in patients’ hospitalization, without a corresponding worsening of the quality of therapy, would provide important benefit. Moreover, since the healing process is remarkably slow, the clinical perception of the phases that lead a chronic wound to complete restoration is often penalized: this effect is dramatically amplified in those cases in which the patient is followed by more than one operator. Therefore, the study of wound healing pathophysiology and the development of new tools for the monitoring of the healing process may represent a possible optimization of the treatment efficacy for these lesions.

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