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A Journal on Physiopathology and Therapy of Chronic Cutaneous Ulcers

Official Journal of the Italian Association for Cutaneous Ulcers
Indexed/Abstracted in: EMBASE, Scopus, Emerging Sources Citation Index

Frequency: Quarterly

ISSN 1721-2596

Online ISSN 1827-1774


Acta Vulnologica 2010 June;8(2):73-9


Treatment of autonomic neuropathy in the prevention of diabetic foot ulcers

Manfredelli S., Martire I., Di Tullio N., Forte A., Lorenzotti A., Chiaravallotti A., Bezzi M., Vietri F., Pastore P. G.

1“F. Durante” Department of Surgery, Umberto I Policlinic, Rome, Italy
2 ASL RM A, Rome, Italy
3 Faculty of Sc.MM.FF.NN., La Sapienza University, Rome, Italy

Aim and methods. The authors take into consideration Difoprev® system, an electrostatic sock positively charged with nanostructured lipid carriers, for the prevention and treatment of autonomic neuropathy in diabetic foot. Patients examined (250) were separated into 2 groups. First was treated with Difoprev® system; the second one with a simple sock.
Results and conclusion. Results obtained demonstrate efficacy and safety of this system with a good skin moisturizing and a reduction of anidrosis and iperkeratosis compared with control group.

language: Italian


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