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A Journal on Physiopathology and Therapy of Chronic Cutaneous Ulcers

Official Journal of the Italian Association for Cutaneous Ulcers
Indexed/Abstracted in: EMBASE, Scopus, Emerging Sources Citation Index




Acta Vulnologica 2009 December;7(4):185-95

language: Italian

Use of a multilayer collagen flap in chronic skin lesions: a posteriori review of clinical data

Ricci E., Cassino R., Moffa F.

Chirurgia 2 Ferite Difficili, Casa di Cura San Luca, Pecetto Torinese, Torino, Italia


Aim. The authors’ purpose was to analysze the results of a series of grafts carried out with multilayer collagen flaps of pig derivation in the treatment of chronic skin lesions of varying etiology.
Methods. The study was carried out retrospectively by analyzing clinical and out-patient records in a series of 472 patients who underwent surgery at the “Difficult wounds” Outpatient Operating Unit. Clinical evaluation parameters were applied. The WBP Score, the evolution assessment and the complications were employed.
Results. The results were interesting in terms of complications and side-effects with a percentage of 0.43% while, if postoperative infections were included, the result stabilised around 3%.
Conclusions. With a 60-day resolution percentage of 34.5% and an optimal 90% preparation of the wound bed at 30 days, the product can be considered effective. The authors point out the limitations of the study in the absence of a control population but the high number of patients analysed still allows an assessment.

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