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A Journal on Physiopathology and Therapy of Chronic Cutaneous Ulcers

Official Journal of the Italian Association for Cutaneous Ulcers
Indexed/Abstracted in: EMBASE, Scopus, Emerging Sources Citation Index




Acta Vulnologica 2008 December;6(4):199-204

language: Italian

Use of the frequency rhythmic electrical modulation system (FREMS) in the treatment of chronic skin ulcers in domiciliary assistance: two case reports

Calcara L. 1, Veneziano G. 1, Vitello S. 1, Di Salvo P. 1, Albano G. 1, Di Silvestre G. 1, Dalia G. 1, Messineo G. 1, Citarrella J. L. 1, Dominguez L. J. 2, Putignano E. 2, Toscano R. 3, Barbagallo M. 2, Oddo G. 1

1 Dipartimento Socio-Sanitario Anziani e ADI – AUSL 6, Palermo, Italia
2 Unità Geriatrica Dipartimento di Medicina Interna Università degli Studi di Palermo, Palermo, Italia
3 Lorenz Biotech, Midolla, Modena, Italia


The management of chronic skin ulcers places considerable direct and indirect costs on the National Healthcare System. In Italy, skin ulcers affect some 2 million persons, indirectly involving family members as well. In those receiving home care, the economic and medical burden is even more relevant and is estimated to grow as the population ages. Chronic skin ulcers in this patient group can often take up to 12 months to heal. This study evaluates the effectiveness of FREMS combined with traditional medications in the treatment of chronic skin ulcers.

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