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Official Journal of the Italian Association for Cutaneous Ulcers
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Acta Vulnologica 2008 June;6(2):79-83

Copyright © 2008 EDIZIONI MINERVA MEDICA

language: Italian

Treatment of deep post-sternotomy wound infection with topical negative pressure therapy and nanocristalline silver: a new strategical therapy?

Cappuccio G. 1, Valesio R. 1, Rinaldi M. 2

1 Unità Operativa Riabilitazione Cardio-Vascolare Casa di Cura Villa Serena Piossasco, Torino, Italia 2 SCDU Divisione di Cardiochirurgia Ospedale S. Giovanni Battista-Molinette Torino, Italia


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The conventional surgical treatment of deep post-sternotomy wound infection/medistinitis is based on different surgical techniques, and the use of topical negative pressure (VAC Therapy) is a very good option. The VAC therapy/nanocristalline silver synergy in terms of antibacterial activity and matrix metalloproteinases (MMPs) reduction has not been studied in depth yet. We describe a case of a 60-year-old patient with a wide post-sternotomy wound infection treated with local VAC therapy and nanocristalline silver association. We think that this association is a valid therapeutic option for the treatment of deep posternotomy wound infections and gives better results than VAC therapy only.

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