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A Journal on Physiopathology and Therapy of Chronic Cutaneous Ulcers

Official Journal of the Italian Association for Cutaneous Ulcers
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Acta Vulnologica 2007 December;5(4):187-93

language: Italian

Vacuum assisted closure therapy: experience of Regina Elena Oncological Orthopaedics Depart-ment in Rome

Zoccali C., Prencipe U., Favale L.

IFO - Istituto Regina Elena, Roma


In Muscle skeletal oncological surgery very difficult and invasive operations are frequently performed. They are necessary to remove with wide margins tumors so that wound breakdown is commune. This problem is a factor often fundamental chousing the opportunity to do or less a specific operation, determining patient survival as well. High incidence of wound dehiscence is connected to infections, particularly commune in pelvic and sacrum surgery, and to ischemic necrosis associated to wide dissections; chemotherapy and radiotherapy, old age, malnutrition, renal failure, obesity, diabetes mellitus and vascular problems can increase risk. Prolonged antibiotic therapy, surgical debridement and coverage flaps are often mandatory to heal surgical access but not always sufficient. VAC-therapy allowed prognosis changing for numerous patient undergone oncological major surgery permitting wound healing before considered impossible, in some case patient survival as well, decreasing inpatient time. Following it is reported our experience using “Vacuum Assisted Closure Therapy”, indication and contraindications found in our practice.

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