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A Journal on Physiopathology and Therapy of Chronic Cutaneous Ulcers

Official Journal of the Italian Association for Cutaneous Ulcers
Indexed/Abstracted in: EMBASE, Scopus, Emerging Sources Citation Index




Acta Vulnologica 2006 September;4(3):107-12

language: Italian

Reconstructive surgery in chronic ulcers of the lower limbs with the use of Integra Derma Regeneration Template

Campitiello F., Della Corte A., Fattopace A., Mancone M.

Unità Operativa di Chirurgia Generale Geriatrica Azienda Ospedaliera Universitaria Seconda Università degli Studi di Napoli, Napoli


The artificial skin graft (Integra Derma Rege-neration Template) on patients treated in our hospital allowed the rapid healing of chronic leg ulcers thus improving considerably patients’ quality of life. The thickness of the skin graft ensures that the healed area is resistant to sustained mechanical stress thus preventing ulcer recurrence. Our experience confirms that reconstructive surgery with the use of Integra in chronic leg ulcers allows: to achieve healing in short time of ulcers that are characterized on one hand by loss of fluid, electrolytes, proteins and often by a progressive blood depletion and on the other hand by the risk of penetration of germs that cause local and systemic infection with subsequent patient’s general condition decay; to improve the quality of life of patients who often need to undergo never ending cycles of day clinics and are socially isolated by their ulcer’s exudate and malodour; to prevent pathologies of the ankle, knee and hip caused by the position taken by the patient trying to relieve his/her pain. From the economic point of view, surgical treatment is also more cost-effective than a correct medical treatment.

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