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A Journal on Physiopathology and Therapy of Chronic Cutaneous Ulcers

Official Journal of the Italian Association for Cutaneous Ulcers
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Acta Vulnologica 2005 June;3(2):71-8

language: Italian

Preventing the occurrence of pressure ulceration in hospitalised elderly patients

Meaume S. 1, Colin D. 2, Barrois B. 3, Bohbot S. 4, Allaert F. A. 5,6

1 Dipartimento di Geriatria Hopital Charles Foix, Ivry sur Seine, Francia
2 Centro di Riabilitazione Centre de L’Arche, le Mans, Francia
3 Dipartimento di Riabilitazione Centre Hospitalier de Gonesse, Francia
4 Laboratoires Urgo, Chenove, Francia
5 Dipartimento di Epidemiologia McGill University, Montreal, Canada
6 Cenbiotech, Dijon, Francia


Aim. The aim of this study was to determine which factors contribute to the development of pressure ulcers and to evaluate the role of topical agents in preventing their occurrence.
Methods. An observational, prospective survey covered 36 care of the elderly wards and involved 1121 patients at high or very high risk of pressure ulceration. The patients, of whom 667 (59.6%) received a gentle application of a topical agent to at-risk areas, were followed up for 8 weeks.
Results. Of the patients, 15.7% developed a pressure ulcer. The use of a corpitolinol 60-based topical agent (Sanyrène/Corpitol) signifi cantly reduced the incidence of pelvic pressure ulcers (P=0.04) when used with recognised prevention strategies. This was identified by undertaking a logistic regression analysis. The resulting odds ratio of 0.61 indicates that the intervention helped to reduce the number of pressure ulcers by 40%.
Conclusion. The results of this observational study can provide a useful guide to the design of further randomised controlled trials.

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