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A Journal on Physiopathology and Therapy of Chronic Cutaneous Ulcers

Official Journal of the Italian Association for Cutaneous Ulcers
Indexed/Abstracted in: EMBASE, Scopus, Emerging Sources Citation Index



Acta Vulnologica 2003 April;1(0):19-24

language: Italian

Effects of the application procedure on the in vivo antimicrobic effectiveness of an antiseptic solution

Masina M. 1, Fini R. 2, Mazza C. 2, Lannichella A. 1

1 Dipartimento Geriatrico, Ospedale Bentivoglio, AUSL BO Nord, Bologna;
2 Laboratorio Analisi, Ospedale Bentivoglio, AUSL BO Nord, Bologna


AIM: Critically colonised chronic cutaneous ulcers in which the aggressive potential of microbes is about to overcome the patient’s defences have been studied.
METHODS: The effectiveness of applying gauze soaked in 150 ml of 0.057% hypochlorite solution was compared with the use by dropping of a similar quantity of antiseptic.
RESULTS: Compared to simple irrigation, the prolonged application of antiseptic-soaked gauze seems to determine a better effect of reducing the bacterial load (ANOVA p<0.057) although it leads to an increase in nursing time.
CONCLUSION: The results confirm that the use of antiseptic substances cannot be a routine procedure but requires the recognition on the part of the operator of a specific clinical condition of critical colonisation and/or of infection and the respect for appropriate application procedures.

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