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A Journal on Phlebology

Official Journal of the Italian College of Phlebology
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Acta Phlebologica 2010 August;11(2):41-3

language: English

The calf vein thrombosis: prevalence, spreading, history and treatment

Antignani P. L., Allegra C.

Department of Angiology, S. Giovanni Hospital, Rome, Italy


The distal vein thrombosis (DVT) is a particular disease poorly studied and actually without consensus on the diagnostic evaluation and the necessary treatment. Sometimes this disease has a good prognosis, but it can extend to proximal veins and even progress to pulmonary embolism, especially if it is bilateral. The main diagnostic test is color Duplex-Doppler evaluation, especially in expertise hands and together with compression test. Sensibility and specificity of CUS are 88% and 95%, compared to phlebography. Serial ultrasounds have two objectives: the first is the diagnosis of distal thrombosis, the second is the evaluation of thrombosis progression to proximal vein. The natural history of this disease is poorly documented and there is no consensus on the necessity of screening and treating patients presenting with isolated distal DVT. Some authors use oral anticoagulants, others prefer performing serial echo-color-Doppler before starting therapy. Recent clinical evidences suggest the use of low weight heparin.

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